The role involves designing and executing experiments using molecular cloning, western blotting, and mammalian cell culture, alongside applying CRISPR-Cas9 gene editing to model disease-relevant mutations. Responsibilities also include performing and analyzing single-cell RNA sequencing, developing synthetic biology platforms, contributing to murine leukemia models, presenting findings, and mentoring junior staff.
Requirements summary
Candidates must possess a PhD in a relevant field such as cancer biology, molecular biology, or bioengineering, and have a minimum of two years of relevant research experience by the time of employment. Essential qualifications include demonstrated productivity via publications and proficiency in core molecular biology techniques and mammalian cell culture.
The Department of Medical Oncology at West Virginia University is currently accepting applications for a Post Doctoral Research Fellow with the WVU Cancer Institute - Hematopoietic Malignancies Program About the Opportunity West Virginia University invites applications for a Postdoctoral Research Fellow to join a dynamic and interdisciplinary research team within the WVU Cancer Institute’s Hematopoietic Malignancies Program. The lab investigates the cellular and molecular mechanisms governing the bone marrow microenvironment, with a particular focus on mesenchymal stem cell-derived exosomes and their role in hematologic malignancies. This position offers a unique opportunity to contribute to cutting-edge cancer biology research using a combination of molecular biology, synthetic biology, and single-cell technologies. The successful candidate will work in a collaborative environment that bridges basic science with translational applications, including therapeutic development and biomarker discovery. Research Focus The lab integrates diverse methodologies to explore:
The functional role of bone marrow stromal cells in leukemia progression
Exosome-mediated intercellular communication
Genetic and epigenetic regulation of hematopoietic stem cells
Novel therapeutic strategies using synthetic biology and CRISPR-based tools We strongly believe in work-life balance and keeping time for things we love outside our work. WVU offers generous benefits, including:
37.5-hour work week
13 paid holidays (staff holiday calendar)
24 annual leave (vacation) days per year (employee leave)
18 sick days per year (for when you’re ill, for when you need time to care for sick family, for your own, or your family’s, regularly scheduled medical appointments. Who is family for the purpose of this leave? A lot of people in your life including immediate relatives and in-laws as well as others considered to be members of your household living under the same roof)
WVU offers a range of health insurance and other benefits
401(a) retirement savings with 6%25 employee contribution match, eligibility to continue health insurance, and other retiree perks. Looking for more retirement benefits information? Check out retirement health insurance benefits, retirement income, and FAQ’s.
Wellness programs What You'll Do
Design and execute experiments involving molecular cloning, western blotting, and mammalian cell culture
Benefits
Health insurance
Paid holidays
Wellness programs
Sick days
Annual leave
37.5-hour work week
Eligibility to continue health insurance
Retiree perks
401(a) retirement savings with 6%25 employee contribution match
Apply CRISPR-Cas9 gene editing to model disease-relevant mutations
Perform and analyze single-cell RNA sequencing and other high-throughput assays
Develop and utilize synthetic biology platforms for functional screening
Contribute to the development and characterization of murine models of leukemia
Present findings at national/international conferences and publish in peer-reviewed journals
Mentor junior lab members and collaborate across disciplines
PhD in cancer biology, molecular biology, biochemistry, stem cell biology, synthetic biology, bioengineering, or a related field
Minimum of two (2) years of relevant research experience
All qualifications must be met by the time of employment.
Knowledge, Skills and Abilities
Demonstrated productivity through a strong publication record
Proficiency in core molecular biology techniques and mammalian cell culture
Interest in translational research and therapeutic innovation
Preferred Qualifications
Experience with single-cell sequencing platforms (e.g., 10x Genomics)
Familiarity with in vivo models of hematologic malignancies
Background in extracellular vesicle biology or stromal cell signaling
