Postdoctoral Research Associate - Oncology

Position Summary

Postdoctoral Research (Scholar or Associate) Position Open in the Jaebok Choi Lab in Department of Medicine, Division of Oncology. Area of expertise: Transplant Immunology focused on T cells. The Choi Lab is seeking a postdoctoral researcher to work on T cell biology in mouse models of diseases, including, but not limited to, graft-vs-host disease (GvHD), inflammatory bowel disease (IBD), and/or experimental autoimmune encephalomyelitis (EAE). Using unbiased genome-wide CRISPR/Cas9 guide RNA library screens and whole kinome analyses, we have identified promising novel therapeutic targets such as VLDLR, GAS6/TAM, and PKN1 whose targeting may separate the inflammatory diseases from the beneficial healthy immune responses, such as graft-vs-leukemia/tumor effects, anti-tumor and anti-infection responses. For translational approaches, the postdoctoral researcher may occasionally analyze human patient samples. In addition to high-quality research facilities, career and professional development training for postdoctoral researchers is provided through the Career Center, Teaching Center, Office of Postdoctoral Affairs, and campus groups.

Job Description: Primary

Duties & Responsibilities

Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/. Please see departmental websites for the more information at https://profiles.wustl.edu/en/persons/jaebok-choi/ and https://oncology.wustl.edu/people/jaebok-choi-phd/. Trains under the supervision of a faculty mentor including (but not limited to): Manages their own project, which should lead to a first author publication. Develops expertise in T cell biology, mouse models of GvHD/GvL, IBD, or EAE, CRISPR/Cas9 guide RNA library screening, bioluminescence imaging, intestinal organoids, and multicolor flow cytometry. Develops proficiency in career skills, including writing, public speaking, networking, and critical evaluation of scientific literature. Presents scientific work both inside and outside the University with excellent oral communication skills. Assists with grant preparation and reporting. Prepares and submits papers on research. Assists in the design of research experiments. Evaluates research findings and assists in the reporting of the results. Conscientious discharge of their research responsibilities. Maintains conformity with ethical standards in research. Maintains compliance with good laboratory practice including the maintenance of adequate research records. Engages in open and timely discussion with their mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications. Collegial conduct towards co-trainees, staff members and members of the research group. Adherence to all applicable University policies, procedures and regulations. All data, research records and materials and other intellectual property generated in University laboratories remain the property of the University. Working Conditions: This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range

Base pay is commensurate with experience. Applicant Special Instructions: Interested candidates should submit their curriculum vitae, statement of research interests and contact information of three references via e-mail to Dr. Jaebok Choi at jchoi25@wustl.edu. The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time. Required Qualifications Education: Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree. Certifications/Professional Licenses: No specific certification/professional license is required for this position. Work Experience: No specific work experience is required for this position.

Skills

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• License: A driver's license is not required for this position.
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• WashU, postdoctoral appointments: Have a 5-year term limit that includes previous experience.

Preferred Qualifications

Education: Ph.D., M.D. or equivalent terminal or doctoral degree. - Cell Biology, Ph.D., M.D. or equivalent terminal or doctoral degree. - Immunology, Ph.D., M.D. or equivalent terminal or doctoral degree. - Molecular Biology Certifications/Professional Licenses: No additional certification/professional licenses unless stated elsewhere in the job posting. Work Experience: No additional work experience unless stated elsewhere in the job posting.

Skills

Collaboration, Data Analysis, Data Interpretations, Experimentation, Genome Editing, Laboratory Operations, Laboratory Techniques, Molecular Biology, Mouse Handling, Multiparameter Flow Cytometry, Primary Cells, Protein Biochemistry, Researching, Results Reporting, Scientific Writing, T Cells Questions For frequently asked questions about the application process, please refer to our External Applicant FAQ. Accommodation If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request. All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship. Pre-Employment Screening All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening. Benefits Statement Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits. EEO Statement Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information. Q: Can I create a job alert to notify me when jobs of interest are posted? A: Yes! After you create a Candidate Home account, you can set up and manage job alerts to be sent to you either daily or weekly, according to the filters you select. You can add, edit, or delete job alerts at any time. You will need to opt in to communications from WashU when you set up your first alert and will only receive alerts for jobs posted after the alert has been created. Set alerts today so you do not miss any new opportunities! Washington University in St. Louis' collective success is significantly attributed to the passion and outstanding efforts of our community. Our staff, faculty and trainees are committed to excellence and dedicated to carrying out our missions of research, teaching and patient care. WashU prides itself on being a place where people matter, and serious work is done. Our people work together in an inclusive community that celebrates diverse perspectives, collaboration and innovation. We are a community of individuals inspired to work together to develop big ideas and tackle challenging problems. We value the well-being of our people. WashU strives to create a positive employee experience where staff, faculty and trainees thrive, both personally and professionally. Our employees find meaning, connection and vitality in their work and life with a healthy work-life balance and support to learn, grow and make an impact at WashU, the community and the world. Useful Links

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Human Resources Benefits Living in St. Louis Frequently Asked Questions Accommodation If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request. Regulatory Postings Know Your Rights: Workplace Discrimination is Illegal Poster (English; Spanish)