Washington University in St. Louis
Location
St. Louis, Missouri
Salary
$48,000 - $86,900 / YEAR
The role involves designing research protocols and conducting experiments to study ER stress-mediated kidney diseases. Responsibilities include data analysis, grant preparation, and publishing research findings in scientific journals.
A Master's degree is required, though a PhD is preferred, along with at least 3 years of experience in laboratory operations. Candidates must be capable of handling biological and chemical hazards and providing care to research animals.
Scheduled Hours 40
ER dysfunction and protein misfolding disease is an emerging field. The overall goals of our research are to delineate the molecular mechanisms underlying ER stress-mediated kidney diseases, including nephrotic syndrome (NS), Alport syndrome, autosomal dominant tubulointerstitial kidney disease (ADTKD) and other acquired forms of ER disease, to develop ER stress biomarkers in human patients, and to identify ER stress modulators. We are using cutting-edge research approaches, including stably transfected or knock-down cells, molecular and cell biology, biochemistry, inducible transgenic, conditional knock-out and CRISPR generated knock-in mouse models, human iPSCs derived from patients, and state-of-the-art in vitro & in vivo imaging techniques. The PI’s research has been funded by multiple grants from NIH, VA Merit and industry. The lab environment is highly supportive for further scientific training and career development. Designs research protocols. Assists in developing and conducting research projects, including experiment design, data analysis and documentation of experiment results.
Job Description: Primary
Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data. Assists with grant preparation and reporting. Performs complex statistical analysis of data collected and writes interpretative reports. Verifies the correctness of the data submitted and makes recommendations based on these analyses. Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers. Solves practical problems relating to difficulties with equipment or test subjects. Suggests technical or procedural improvements in testing methods. Conducts literature searches related to research project. Performs other duties as assigned. Working Conditions: Works in a laboratory environment with potential exposure to biological and chemical hazards. Must be physically able to wear protective equipment and to provide standard care to research animals. The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time. Required Qualifications Education: Master’s degree or combination of education and/or experience may substitute for minimum education. Certifications/Professional Licenses: No specific certification/professional license is required for this position. Work Experience: Laboratory Operations (3 Years) Skills: Not Applicable Driver's License: A driver's license is not required for this position. More About This Job WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.
Education: Ph.D. - Doctor of Philosophy Certifications/Professional Licenses: No additional certification/professional licenses unless stated elsewhere in the job posting. Work Experience: No additional work experience unless stated elsewhere in the job posting.
Human Resources Benefits Living in St. Louis Frequently Asked Questions Accommodation If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request. Regulatory Postings Know Your Rights: Workplace Discrimination is Illegal Poster (English; Spanish)
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