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City of Hope
Overview
Investigate the role of mitochondrial AKT as a regulator of ovarian granulosa cell development during folliculogenesis. Use transgenic mouse models to study how insulin resistance modulates mitochondria and transcriptomes.
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Compensation
Salary not listed
Posted
24 days ago
The role involves conducting tissue culture and functional assays for T cell lines, including cytotoxicity and ELISA. Additionally, the associate will perform multicolor flow cytometry and assist with murine surgical procedures and lab protocol maintenance.
1 month ago
The candidate will conduct tissue culture and T cell functional assays while performing multicolor flow cytometry and data analysis. Additionally, they will assist in murine surgical procedures and maintain laboratory protocols according to GLP standards.
The postdoctoral fellow will independently conduct research on iPSC-based disease models, tumor immunity, and therapeutic target identification using CRISPR screens. Additionally, the role involves supervising research interns, writing research papers, and organizing data for grant applications.
2 months ago
The successful candidate will conduct independent research on hematological malignancies, including iPSC-based disease modeling and CRISPR screening. Additionally, they will supervise research interns, write research papers, and organize data for grant applications.
The physician scientist will conduct independent basic, translational, or clinical research in endocrine tumor or metabolism while maintaining a clinical practice. They will be expected to compete for extramural funding and contribute to the research initiatives of the Department of Diabetes, Endocrinology, and Metabolism.
$300,000 - $400,000 / YEAR
The postdoctoral fellow will join the Deng laboratory to study the homeostasis of uridine and its role in metabolism, focusing on understanding the pathophysiology of obesity, diabetes, and cancer. Research activities involve utilizing genetically engineered mouse models and in vitro systems with approaches like surgical, genetic, cellular, biochemical, imaging, and metabolic flux techniques.
The postdoctoral fellow will join the Deng laboratory to study the homeostasis of uridine and its role in metabolism, focusing on understanding the pathophysiology of obesity, diabetes, and cancer. Research activities involve utilizing genetically engineered mouse models and in vitro systems with state-of-the-art surgical, genetic, cellular, biochemical, imaging, and metabolic flux approaches.
The postdoctoral fellow will join the Deng laboratory to study the homeostasis of uridine and its role in metabolism, investigating its relevance to the pathophysiology of obesity, diabetes, and cancer. Research activities will involve utilizing genetically engineered mouse models and in vitro systems with a combination of advanced surgical, genetic, cellular, biochemical, imaging, and metabolic flux approaches.
The postdoctoral fellow will investigate the homeostasis of uridine and its role in the pathophysiology of obesity, diabetes, and cancer using genetically engineered mouse models and in vitro systems. Research will focus on the role of uridine in disease progression, its physiology in bile and nutrient absorption, and its regulation by ER stress relevant to breast cancer.