Post Doctoral Scholar - Comprehensive Cancer Center

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• Job Title: Post Doctoral Scholar - Comprehensive Cancer Center Department: Medicine | School Biomedical Sciences Cancer Biology and Genetics Dr.
• Yang Gao joined The Ohio State University (OSU) in August 2025 as an Assistant Professor in the Department of Cancer Biology & Genetics, where he is establishing an independent research program.
• Supported by generous start-up funding from OSU and an active NIH K99/R00 award, the Gao Lab provides a strong and stable foundation for scientific discovery.
• We are seeking 2 Postdoctoral Scholars to join our growing team and explore how tumor–immune interactions shape cancer progression and therapy response. 🔬 Our Research At the Gao Lab, we study the tumor ecosystem with a focus on three major themes: The heterogeneity of the immune landscape Mechanisms of therapeutic resistance The role of tumor–host interactions in cancer metastasis Our work aims to uncover why treatment resistance and distant recurrence occur in solid tumors, with a special emphasis on breast cancer.
• Our discoveries so far include showing how myeloid cell heterogeneity contributes to immunotherapy resistance and revealing how the bone microenvironment shapes breast cancer bone metastasis.
• Current projects in the lab: Exploring how neutrophil interferon-stimulated genes regulate the tumor immune microenvironment and response to immunotherapy.
• Mapping the immunosuppressive ecosystems that support breast cancer metastasis in major organs, including bone, lung, liver, and brain.
• Identifying new mechanisms that drive therapeutic resistance in metastatic disease.
• To tackle these questions, we use cutting-edge technologies, including spatial transcriptomics, single-cell multi-omics, tumor immunology, and in vivo genetically engineered mouse models.
• By bringing these approaches together, we strive to generate insights that will translate into better therapies and improved outcomes for patients.
• Required Qualifications Ph.D. in Biomedical Sciences, Oncology, Immunology, Molecular or Cellular Biology, or a related field At least one first-author publication in a relevant research area Experience with animal models, spatial transcriptomics, or multi-omics integration is highly desirable Strong written and oral communication skills; team-oriented and self-motivated We Offer Competitive NIH-scale salary and full OSU benefits Mentorship and career-development support, including guidance for independent fellowships (e.g., NIH K99/R00) ✉️ How to Apply Applications are reviewed on a rolling basis until positions are filled.
• Please include the following documents with your application: A brief cover letter describing your background, research interests, and career goals Curriculum vitae with publication list Contact information for three references Inquiries about this position can be directed to Dr.
• Yang Gao yang.gao@osumc.edu Please include “Application for Postdoctoral Fellow + [Your Name]” in the email subject line.

Additional Information

Location: Biomedical Research Tower (0112) Position Type: Term (Fixed Term) Scheduled Hours: 40 Shift: First Shift Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process. Thank you for your interest in positions at The Ohio State University and Wexner Medical Center. Once you have applied, the most updated information on the status of your application can be found by visiting the Candidate Home section of this site. Please view your submitted applications by logging in and reviewing your status. For answers to additional questions please review the frequently asked questions. The university is an equal opportunity employer, including veterans and disability. Each day, Buckeyes across the state and around the world make a lasting impact. The Ohio State University sets the stage for academic achievement and innovation. It's where friendships are forged, tradition is brought to life and a better global community is built. Our mission is as clear today as it was 150 years ago: to illuminate a pathway to education, research and health care that creates vibrant futures. Faculty and staff build the incomparable Buckeye spirit through collaboration, a strong sense of community and an unwavering commitment to excellence. Our strength comes from our ability to bring out the best in people and learn from Buckeyes of all backgrounds, passions and talents. Ohio State is a dynamic community where opportunity thrives and individuals transform themselves and their world. Positions are available in countless fields and specialties. Ohio State is a top-20 public university, and its Ohio State Wexner Medical Center is one of America’s leading academic health centers. Eligible Ohio State employees receive comprehensive benefits packages, including medical, dental and vision insurance, tuition assistance for employees and their dependents, and state or alternative retirement options with competitive employer contributions. Become a Buckeye and contribute to an incredible legacy that serves to guide our future and shape a better tomorrow.