Washington University in St. Louis
Salary
$48,000 - $86,900 / YEAR
The Staff Scientist will design and execute wet- and dry-lab experiments focusing on CRISPR/Cas9 gene-edited CAR-T cell therapy for hematologic malignancies. Responsibilities include managing data, performing statistical analysis, and preparing research papers for publication.
A Master's degree is required, though a Ph.D. is preferred, along with at least 3 years of experience in laboratory operations. Candidates must be proficient in molecular biology, cell culture, and animal handling techniques.
Scheduled Hours 40
A Staff Scientist position is available in the laboratory of Dr. John DiPersio, with direct reporting to Dr. Jerry Xiang. This position is part of a translational cell therapy program focused on advancing next-generation immunotherapies from discovery through IND-enabling studies and clinical translation. The successful candidate will work at the interface of discovery and translation, contributing to projects involving CRISPR/Cas9 gene-edited CAR-T cell therapy for hematologic malignancies. Ongoing efforts are directed toward IND-enabling studies, providing a unique opportunity to gain hands-on experience in developing cell therapies from bench to clinic. The Staff Scientist will assist in developing and supporting the design and execution of wet- and dry-lab experiments, including the generation and functional evaluation of engineered immune cells in preclinical mouse models. This role involves close collaboration with multidisciplinary teams and offers the chance to contribute meaningfully to projects with direct clinical impact. Our group is highly collaborative and offers a supportive, well-resourced setting with strong opportunities for professional growth.
Job Description: Primary
For more information on the lab please visit https://www.johndipersiolab.com/. Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data. Assists with grant preparation and reporting. Performs complex statistical analysis of data collected and writes interpretative reports. Verifies the correctness of the data submitted and makes recommendations based on these analyses. Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers. Solves practical problems relating to difficulties with equipment or test subjects. Suggests technical or procedural improvements in testing methods. Conducts literature searches related to research project. Performs other duties as assigned. Working Conditions: Works in a laboratory environment with potential exposure to biological and chemical hazards. Must be physically able to wear protective equipment and to provide standard care to research animals. The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time. Required Qualifications Education: Master’s degree or combination of education and/or experience may substitute for minimum education. Certifications/Professional Licenses: No specific certification/professional license is required for this position. Work Experience: Laboratory Operations (3 Years) Skills: Not Applicable Driver's License: A driver's license is not required for this position. More About This Job WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.
Education: Ph.D. - Doctor of Philosophy Certifications/Professional Licenses: No additional certification/professional licenses unless stated elsewhere in the job posting. Work Experience: No additional work experience unless stated elsewhere in the job posting.
Human Resources Benefits Living in St. Louis Frequently Asked Questions Accommodation If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request. Regulatory Postings Know Your Rights: Workplace Discrimination is Illegal Poster (English; Spanish)
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