The role involves processing human surgical specimens for omic technologies and maintaining genetically engineered mouse colonies. The technician will conduct various in vitro and in vivo assays to support research on renal cell carcinoma.
Requirements summary
A Bachelor's degree in biology or life sciences is required. Candidates must be comfortable working with animals and possess basic laboratory skills with strong attention to detail.
Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe.
Exciting
Opportunity at
Memorial
Sloan
Kettering
Cancer
Center: Join the A. Ari Hakimi Lab as a Research Technician! The Hakimi Lab at Memorial Sloan Kettering Cancer Center studies the immune and metabolic regulation of the renal cell carcinoma (RCC) microenvironment, to uncover critical mechanisms and biomarkers of response to current systemic therapies that include immune checkpoint blockade and angiogenesis-targeted therapies. We are a highly translationally-minded lab with combined expertise that effectively bridges clinical and preclinical research. We collaborate widely on interests in T cell biology under immune checkpoint blockade therapy, CAR-T cell engineering, as well as genomic and epidemiological (sex and obesity) drivers of immuno-metabolic dysregulation in cancer. Our lab also engineers novel mouse models of RCC that more accurately reflect the genomic profiles of human kidney cancer, providing important tools for the study of heterogenous RCC subtypes in mice with fully functional immune systems. A new hire would work flexibly alongside other research technicians to expand our internal human biobank with a focus on processing fresh surgical specimens for cutting edge omic technoliges, as well as maintaining our genetically engineered mouse colonies for experimentation. Our lab is commited to fostering a rich learning environment, thus there will be an opportunity for the successful candidate to nurture an independent research project under postdoc mentorship. The new hire will be expected to master many in vitro and in vivo techniques and will receive broad training and mentorship at the forefront of translational medicine. Due to these training efforts, we require a minimum 2 year commitment.
Role
Overview:
Techniques &
Assays: Conduct common and apecialised assays including mammalian cell culture, organoid culture, mouse genotyping using DNA electrophoresis, western blotting, flow cytometry processing, sorting and acquisition, human and mouse tissue processing for single cell RNA-sequencing, PBMC isolation and cryopreservation, CRISPR/cas9 genome engineering, cell counting.
Animal
Handling: Conduct animal studies, including mouse handling, breeding, injections (intraperitoneal, intravenous, subcutaneous), kidney ultrasound imaging, animal autopsies, tissue and blood collection. Poential for mouse renal injection surgical training.
Laboratory
Support: Prepare and maintain lab equipment, instruments, solutions, and other essential supplies.
Data
Management: Record and analyze research data, prepare reports, and provide updates to the research team in lab meetings.
Collaboration
Assist peers and researchers with ongoing projects, fostering a team-oriented, supportive environment.
Key
Qualifications: Bachelor's degree in biology/life sciences. Basic laboratory skills. Comfort working with animals.
Core
Skills: Attention to detail and strong record-keeping habits. Ability to follow protocols while troubleshooting when needed. Team-oriented approach to supporting postdocs and fellow researchers. Adaptability in a dynamic lab environment.
Additional Information
Location: NYC; Zuckerman Research Center Schedule: 37.5 hours per week (onsite) Helpful Links: The Hakimi Lab Compensation Philosophy Benefits Pay Range: $26.77 - $40.05 FSLA Status: Non-Exempt Closing: At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills. MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment. Our multi-disciplinary teams work together to provide exceptional patient care, develop innovative research, and deliver outstanding educational programs. Learn More The people of MSK make this an incredible place to work, grow and make a difference. Discover what makes us unique
