Provide scientific leadership to drive early discovery research in osteoporosis, including target evaluation and mechanism-based therapeutic strategies. Maintain a hands-on laboratory presence to execute in vitro and in vivo models for preclinical drug discovery and target validation.
Requirements summary
Requires a Ph.D. in a STEM field with 2+ years of experience or a Master's degree with 8+ years of relevant industry experience. Deep expertise in bone biology and hands-on experience with preclinical osteoporosis models are essential.
postgraduate degreeMentorshipPharmacologyCross-functional collaborationData analysisScientific communicationScientific leadershipExperimental designIn vitro modelsIn vivo modelsTarget validationBone biologySkeletal biologyMechanism-of-action studiesPreclinical drug discoveryOsteoporosis researchEndocrine regulation
Job description
At Lilly, we unite caring with discovery to make life better for people around the world.
We are a global healthcare leader headquartered in Indianapolis, Indiana.
Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism.
We give our best effort to our work, and we put people first.
We’re looking for people who are determined to make life better for people around the world.
At Lilly, we unite caring with discovery to make life better for people around the world.
As a global healthcare leader headquartered in Indianapolis, Indiana, we are committed to advancing innovative medicines in areas of high unmet medical need.
With a strong track record in bone and metabolic diseases, Lilly is continuing to build a differentiated discovery portfolio in osteoporosis and age‑related skeletal disorders.
We are seeking an experienced discovery biologist to provide scientific leadership and hands‑on expertise to help shape early research strategy and advance novel therapeutic concepts for osteoporosis.
This role offers the opportunity to drive mechanism‑based discovery while maintaining direct experimental engagement within a highly collaborative research environment.
Key Responsibilities Provide independent scientific and technical leadership to drive early discovery research focused on osteoporosis and skeletal biology, including target evaluation, hypothesis generation, and mechanism‑based therapeutic strategies.
Maintain a hands‑on laboratory presence, developing and executing in vitro, ex vivo, and in vivo models and assays to support preclinical drug discovery.
Design and conduct experiments for target validation, preclinical pharmacology, and mechanism‑of‑action studies, with a focus on bone remodeling and skeletal integrity.
Contribute as a core biology lead within cross‑functional project teams, partnering closely with medicinal chemistry, translational, and safety colleagues.
Function independently while contributing effectively within a team‑oriented lab environment.
Provide scientific mentorship and supervision to 1–2 scientists, including performance feedback and career development support as appropriate.
Benefits
401(k)
Dental insurance
Vision insurance
Medical insurance
Life insurance
Flexible spending accounts
Employee assistance program
Pension
Vacation benefits
Time off
Prescription drug benefits
Fitness benefits
Death benefits
Employee clubs and activities
Leave of absence
Ensure high data quality and scientific rigor, including accurate documentation, independent data analysis, and clear communication of results in written and oral formats.
Perform work in full compliance with Lilly Research Policies, safety requirements, and training expectations.
Minimum Qualifications
Ph.D. in biology, biophysics, biochemistry, bioengineering, or related STEM field; OR Master's degree in biology, biophysics, biochemistry, bioengineering, or related STEM field with 8+ years of relevant industry experience Additional Skills / Preferred Qualifications
Deep expertise in bone biology, including osteoblast/osteoclast biology, bone remodeling, or endocrine regulation of skeletal health. 2 years Post Doc training Hands‑on experience with preclinical in vivo osteoporosis models, and supporting in vitro and ex vivo systems. Track record of implementing or advancing novel assays or research platforms to answer key biological questions. Strong scientific communication skills and experience presenting data in multidisciplinary team settings. Demonstrated initiative, sound scientific judgment, and comfort operating under ambiguity. experience spanning both osteoporosis and Women’s health related disorders, such as endometriosis, preeclampsia, PCOS and menopause related preclinical research is a plus. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $138,000 - $224,400 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people. We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe! #WeAreLilly
